Protein Complex Stoichiometry
The function, activity and location of protein complexes can be regulated via post-translational modification of key subunits but also through composition of its subunits.
Qualitative and quantitative analysis of protein complexes using mass spectrometry is independent of antibodies and enables further insight into the regulation of protein complexes, metabolic pathways and signalling cascades in their native environment.
Our service includes:
- Analysis of protein complex components in whole cell lysates or after immunoprecipitation
- Determination of subunit stoichiometry
- Quantitative measurement of protein complex subunits
Protein analysis with high sensitivity and specificity
Ultra-sensitive detection with high-end instruments
Assistance at every step of the project, from sample extraction, digestion to MS analysis
Complete reporting including all acquired data, extraction and digestion protocols, MS settings