Proteomics methods

Overview about the most frequently used research technologies in quantitative proteomics.

Method	Advantages	Drawbacks
QconCAT	Digest control Accurate Multiplexing Cost-effective High stability	Complex design
Synthetic peptides (e.g. AQUA)	Cost-effective	Possible resolubilization problems High work effort preparing peptide mixtures Low stability No digest control
QPrEST	Cost-effective	Limited peptide selection No custom design High work effort preparing peptide mixtures
Complete labeled protein	Accurate High stability Digest control	Expensive High work effort for protein expression