Protein quantification from biological samples before, during and at the end of clinical studies is employed to support patient selection, monitoring disease states, progression and study outcome.

 

Protein quantification remains a challenge, especially when no specific antibodies are available.  New antibody assay development is usually a long term and expensive project. Hundreds of samples are investigated in every clinical study with multiple proteins in each single sample, thus a multiplexing technology is an essential requirement. Clinical studies data need to be comparable and reproducible between laboratories, clinical study sites and even cross-globally. Modern diagnostic tend to apply less invasive methods and often need to deal with very small sample amount.

QconCAT technology corresponds to all clinical study protein quantification assay requirements Multiplexing of up to 100 proteins Absolute quantification Small sample volume Antibody-free Cost-efficient Highly reproducible and transferable results Applicable to sample of any nature (blood, urine, CSF, tissue sample, etc)

 

Depending on your clinical data project requirements we suggest

QconCAT as a customized kit

Based on a detailed analysis of your requirements, we will provide you with an isotope-labeled QconCAT protein mixture which you can use as a control kit on your mass spectrometry instrumentation to make protein quantification of your samples.

QconCAT full service

If you are not equipped to perform mass spectrometer or if you want to save time and resources, we offer a full service where we create the QconCAT and perform the protein quantification of your samples in-house.

 

Contact our experts for more details and get professional advice on your protein quantification assay